Peritoneal adhesions: Facing the enemy
نویسندگان
چکیده
منابع مشابه
Peritoneal closure and adhesions.
We have read the debate on peritoneal closure by Cheong et al. with interest (Cheong et al., 2001). The authors state that the long term benefits and hazards of non-closure of the peritoneum are unknown, and expect adhesion related problems. Among the various outcome measures concerning long-term morbidity, adhesion formation/reformation is probably one of the most important ones. The presence ...
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Peritoneal adhesions represent an important clinical challenge in gastrointestinal surgery. Peritoneal adhesions are a consequence of peritoneal irritation by infection or surgical trauma, and may be considered as the pathological part of healing following any peritoneal injury, particularly due to abdominal surgery. The balance between fibrin deposition and degradation is critical in determini...
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The most common cause of intraperitoneal adhesions which may result in infertility and intestinal obstruction is previous abdominal surgery. Surgical trauma of the peritoneum in the absence of infection elicits a rapid and transient influx of polymorphonuclear leukocytes (PMN) into the peritoneal cavity. The role of neutrophils in intraperitoneal adhesion formation has not been studied. We aime...
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A study was designed to investigate the possibility of reducing peritoneal adhesion formation in mice by pretreatment with allopurinol. Allopurinol, at a dose of 35 mg/kg of body weight/d significantly reduced the severity of peritoneal adhesions (P < .001), and also the neutrophil response to ischemia (P < .05). Tissue myeloperoxidase activity at the site of ischemic injury was significantly l...
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ژورنال
عنوان ژورنال: International Journal of Surgery
سال: 2008
ISSN: 1743-9191
DOI: 10.1016/j.ijsu.2007.05.010